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Doxepin 10/25/75mg

DOXEPIN (Zonalon®) relieves the itching that is associated with certain types of skin disorders

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What is doxepin?

Doxepin is an antidepressant. Doxepin is used to treat depression or anxiety. It may also be used to treat other diseases, such as gastrointestinal ulceration and other GI-problems (eg, irritable bowel syndrome).

Alert your doctor if any of these apply to you:

  • you are taking dofetilide, clonidine, cisapride, H1 antagonists (eg, astemizole, terffenadine), or ibutilide, or you have taken a monoamine oxidase (MAO) inhibitor (eg, urazolidone, phenelzine, isocarboxiad) within the last two weeks
  • you are allergic to any ingredient in doxepin, any other medication, foods, dyes, preservatives, or other substances
  • you have certain prostate problems (eg, asymptomatic prostatic hypertrophy), trouble urinating or glaucoma
  • you have blood problems (eg, porphyria), other mental or mood problems, suicidal thoughts or attempts, prostate problems (eg, benign prostatic hypertrophy (BPH)), alcohol abuse, overactive thyroid, seizures (eg, epilepsy), or history of heart problems
  • you are pregnant, planning to become pregnant, or are breast-feeding
  • you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

How to use:

Strictly follow your doctor's insructions. Advert to medicine label to get the exact dosing instructions.
  • Medication Guide is an additional patient information sheet. It comes with the doxepin.
  • You may take doxepin either with or without food.
  • Some side effects, such as drowsiness may be reduced if you take doxepin at bedtime.
  • Don't stop taking fluvoxamine until your doctor said so.
  • If you miss a dose, and you are prescribed to take one dose daily, take the missed dose the same day. If you are taking more than one dose daily, skip thó missed dose and go back to your regular dosing schedule. Never take two doses at one stroke.

Saety issues:

  • It is known, that doxepin may cause drowsiness or dizziness. Until you know your reaction to fluvoxamine, aviod driving, operating machinery or doing something else that requires mental alertness.
  • Avoid drinking alcohol or taking other antidepressants to preclude mixing and effects adding.
  • Some children or teenagers may experience the increase of suicidal thoughts and behaviors. The risk increases if individual have bipolar ilness (also called manic-depressive illness), a family history of bipolar illness, or a history of attempting suicide. Pay close attention to changes in moods or actions, especially if changes occur suddenly.

What drug(s) interact with doxepin?

  • MAO inhibitors (eg, phenelzine, furazolidone, isocarboxazid)
  • selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine, sertraline)
  • guanfacine
  • guanethidine
  • guanadrel
  • clonidine
  • phenothiazines (eg, chlorpromazine, thioridazine)
  • mibefradil
  • tramadol
  • sympathomimetics (eg, pseudoephedrine, phenylephrine)
  • sulfonylureas (eg, tolazamide, glipizide)
  • cimetidine
  • carbamazepine
  • ibutilide
  • H1 antagonists (eg, terfenadine, astemizole)
  • antifungal medicines (eg, terbinaine, fluconazole)
  • dofetilide
  • cisapride
  • anticoagulants (eg, warfarin)
  • antiarrythmics (eg, flecainide, propafenone, quinidine)

Possible side effects:

If you experience these side effects, you should contact your doctor immediately:
  • yellowing of skin or eyes
  • severe allergic reactions (tightness in the chest, difficulty breathing, hives, rash, swelling of the mouth, face , lips, or tongue)
  • unusual bleeding or bruising
  • abnormal movements
  • twitching of the face or tongue
  • agressive or bizzare behavior
  • trouble sleeping
  • agitation
  • anxiety
  • sore throat or fever
  • blurred vision or other vision changes
  • shakiness
  • seizures (convulsions)
  • chest pain
  • ringing in the ears
  • panic atacks
  • restlessness or nervousness
  • constipation
  • difficulty speaking or swallowing
  • mood swings
  • loss of balance
  • disorientation
  • eye pain
  • hostility
  • irritability
  • fainting
  • arrythmic heartbeat
  • hair loss
  • hallucinations
These side effects usually don't require medical attention (but you should contact your doctor if they continue or are bothersome):
  • weight gain
  • appetite loss
  • weakness
  • diarrhea
  • vomiting
  • dizziness
  • drowsiness
  • urinary retention
  • dry mouth
  • unpleasant taste
  • excess sweating
  • nausea
  • indigestion
  • headache
  • heartburn
  • increased appetite

What is the shelf life of the pills?

  • The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

What is a generic pill?

Generic drug (pl. generic drugs, short: generics) is a drug which is produced and distributed without a brand name. A generic must contain the same active ingredients as the original formulation. In most cases, it is considered bioequivalent to the brand name counterpart with respect to pharmacokinetic and pharmacodynamic properties.

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