GLIMEPIRIDE (Amaryl) is the first III generation sulphonyl urea it is a very potent sulphonyl urea with long duration of action.Glimepiride distinctly lower the blood glucose level by both defects of NIDDM, by stimulating pancreatic beta cells to produce more insulin and induced increased activity of peripheral insulin intra cellular receptor.
Glimepiride is the first III generation sulphonylurea. It distinctly lowers the blood glucose level by both defects of NIDDM, by stimulating pancreatic beta cells to produce more insulin and induced increased activity of peripheral insulin intra cellular receptor.
Tell your doctor if any of these apply to you:
you are pregnant, planning to become pregnant, or are breast-feeding
you have diabetic ketoacidosis
you have liver or kidney disease
you are allergic to Glimepiride, any other medicine, dyes, foods, preservatives, or other substances
you have recently had major surgery
you have thyroid disease
you have severe injury or infection
Safety issues:
Visit your doctor for regular checks on your progress
Do not skip meals
Regularly check your blood sugar
Make sure family members know that you can choke if you eat or drink when you have serious symptoms of blood sugar
Medications that may cause changes (increase or decrease) in blood sugar:
water pills (diuretics)
thyroid hormones
alcohol containing beverages
ACE inhibitors
tegaserod
tacrolimus
antiretroviral protease inhibitors
sulfanomides, medicines for infection
aspirin and aspirin-like drugs
steroid medicines
baclofen
some herbal dietary supplement
beta-blockers
quinolone antibiotics
certain medicines used for mental depression, emotional, or psychotic disturbances
phenytoin
chromium
pentamidine
cisapride
clonidine
pentamidine
cyclosporine
octreotide
diazoxide
disopyramide
epinephrine
female hormones, such as birth control pills
nicotine
fibric acid derivatives
niacin
glucagon
medicines for allergies, asthma, cold, or cough
growth hormone (somatropin)
guanethidine
medications to suppress appetite or for weight loss
male hormones or anabolic steroids
lithium
isoniazid
metoclopramide
Possible side effects:
If you experience these side effects, you should contact your doctor immediately:
unusual tiredness or weakness
anxiety or nervousness, confusion, difficulty concentrating
unusual bleeding or bruising
blurred vision
breathing difficultiess or excessive phlegm
tremor or shakiness
cold sweats, increased sweating
seizures (convulsions)
cool, pale skin
fever, chills, sore throat
coughing up blood
fast heartbeat, palpitations, chest pain
dark yellow or brown urine
dizziness, drowsiness
excessive hunger
These side effects usually don't require medical attention (but you should contact your doctor if they continue or are bothersome):
skin rash, redness, swelling, or itching
diarrhea
nausea, vomiting
headache
increased sensitivity to the sun
heartburn, stomach discomfort
What is the shelf life of the pills?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
What is a generic pill?
Generic drug (pl. generic drugs, short: generics) is a drug which is produced and distributed without a brand name. A generic must contain the same active ingredients as the original formulation. In most cases, it is considered bioequivalent to the brand name counterpart with respect to pharmacokinetic and pharmacodynamic properties.
